Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma
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چکیده
منابع مشابه
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.
The growth of many cancers depends on self-renewing cells called cancer stem cells or tumor-propagating cells (TPCs). In human brain tumors, cells expressing the stem cell marker CD133 have been implicated as TPCs. Here we show that tumors from a model of medulloblastoma, the Patched mutant mouse, are propagated not by CD133(+) cells but by cells expressing the progenitor markers Math1 and CD15...
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2009
ISSN: 1535-6108
DOI: 10.1016/j.ccr.2009.08.009